Program OSSD 2013

 

PROGRAM OVERVIEW

SPECIAL LECTURES

¥   Bruce McEwen PhD, Rockefeller University, KEYNOTE:
ÔSex, Stress and the Brain:  From Serendipity to Clinical RelevanceÕ

¥   Alice Dreger, PhD, Northwestern University, SPECIAL GUEST LECTURE: ÔThe use of prenatal dexamethasone for congenital adrenal hyperplasiaÕ

¥   Eric Vilain MD/PhD, UCLA, CAPSTONE LECTURE: ÔGender and genetics of sexual developmentÕ

 

WORKSHOP

¥   ÒSex Differences 101Ó: From biological basics to biomarkers

Chair: DeLisa Fairweather PhD (Johns Hopkins University)

 

SYMPOSIA

¥   Elizabeth Young New Investigator Symposium, Chair: Geert de Vries, PhD, Georgia State University)

¥   Presidential Symposium: Sex Differences in Autism (Sponsored by Autism Speaks), Co-Chairs: Rosanna Weksberg MD/PhD, University of Toronto and Peter Szatmari, MD, McMaster University

¥   Symposium I: Diverse roles of gonadal hormones in the pathology and treatment of epilepsy in men and women, Chair: Helen Scharfman, PhD, NYU Langone Medical Center

¥   Symposium II: Infections and heart disease, Chair: Sally Huber, PhD, University of Vermont

¥   Symposium III: Psychoimmunology of mental illness (in memory of S. Zalcman) Co-Chairs: Kevin Beck, PhD, University of Medicine & Dentistry of NJ/East Orange VA Med Center and Gretchen Neigh, PhD, Emory University

¥   Symposium IV: Sex Differences in Cardiac Arrhythmias, Chair: Glenna Bett, PhD, University of Buffalo

¥   Symposium V: Clinical Considerations of Sex and Gender in Clinical Practice: Promise, Potential, and Pitfalls, Chair: Marjorie Jenkins, MD, Texas Tech Health Sciences University

¥   Symposium VI: Sex and Gender in Cardiovascular-Renal Physiology and Pathophysiology, Chair: Jane Recklehoff, PhD, University of Mississippi Medical Center

¥   Symposium VII: Pain Management in Cancer, Chair: Karen Berkley, PhD, Florida State University

¥   Symposium VlII: Sex differences in gene expression, Chair: Christine Disteche, PhD, University of Washington

¥   Symposium IX: Causes and consequences of sex differences in multiple sclerosis, Chairs: R. Hal Scofield, MD, University of Oklahoma Health Sciences Center, and Sabra Klein, PhD, Johns Hopkins University

¥   Symposium X: Influence of Sex/Sex Hormones on the GutÕs Role as Guardian of Health, Chair: Lisa Kilpatrick, PhD, UCLA

¥   Symposium XI: Centers for Sex Difference Research, Chair: Janine Clayton, MD, NIH: Office of Research on WomenÕs Health

 

POSTER SESSIONS

Poster Session I, Neurology, Immunology, Bone, Cancer, Liver and Metabolism, Pain, Development and Aging

Poster Session II, Cardiovascular, Psychiatry, Urology, Sexual Differentiation, Substance Abuse, Other

 

PROGRAM SCHEDULE

¥   Thursday, April 25th Breakfast (8:00 – 8:30); Pre-Conference Workshop (8:30 – 12:00); Registration & Exhibit set up (12:00 – 1:00); Welcome and Introductions (1:00 – 1:15); Keynote (1:15 – 2:15); Elizabeth Young New Investigator Symposium (2:15 – 3:15); Break (3:15 – 3:30); Presidential Symposium (3:30 – 5:30); Poster Session I (5:30 – 8:00); Welcoming Reception (8:00)

¥   Friday, April 26th Breakfast (7:30 – 8:15); Parallel Symposia I and II; (8:15 – 10:15); Coffee Break (posters and exhibits open) (10:15-10:30); Parallel Symposia III and IV (10:30 – 12:30); Lunch (posters and exhibits open) (12:30 – 2:30); Parallel Symposia V and VI (2:30 – 4:30); Special Guest Lecture (4:30 – 5:30); Poster Session II (5:30 – 8:00)

¥   Saturday, April 27th Breakfast (7:30 – 8:15); Parallel Symposia VII and VIII; (8:15 – 10:15); Coffee Break (10:15-10:30); Parallel Symposia IX and X (10:30 – 12:30); Lunch (12:30 – 2:30); Plenary Symposium XI (2:30 – 4:30); Capstone Lecture (4:30  – 5:30); General OSSD Membership Meeting (5:30 – 6:30); Closing Ceremonies (Awards) and Banquet (7:00)

 

PROGRAM DETAILS

THURSDAY, April 25th

8:00 – 8:30           Breakfast

 

8:30 – 12:00         Pre-Conference Workshop

Sex Differences 101Ó: From biological basics to biomarkers

Chair: DeLisa Fairweather PhD (Johns Hopkins University)

 

12:00                   OSSD Meeting Opens

 

12:00 – 1:00         Registration & Exhibit set up

 

1:00 – 1:15           Welcome and Introductions

 

1:15 – 2:15           Keynote

Bruce McEwen PhD (Rockefeller University) Sex, Stress and the Brain: From Serendipity to Clinical Relevance

 

2:15 – 3:15           Elizabeth Young New Investigator Symposium

Chair: Geert de Vries PhD, (Georgia State University)

 

3:15 – 3:30           Break

 

3:30 – 5:30           Presidential Symposium

Sex Differences in Autism (Sponsored by Autism Speaks)

Chairs: Rosanna Weksberg MD/PhD (University of Toronto) and Peter Szatmari MD, (McMaster University)

¥   Peter Szatmari MD (McMaster University) Re-thinking Sex Differences in Autism Spectrum Disorders

¥   Aravinda Chakravarti PhD (Johns Hopkins University) Testing Genetic Etiologies of Sex Differences in Disease Incidence

¥   Stephan Sanders MD (Yale University) Evidence for Sex Bias Etiologies in Exome and Copy Number Variation (CNV) Data

¥   Janine LaSalle PhD (UC-Davis) Epigenetic Sex Differences from Environmental Exposures Relevant to Autism Spectrum Disorders

 

5:30 – 8:00           Poster Session I

 

8:00                     Welcoming Reception

 

FRIDAY, April 26th

7:30 – 8:15           Breakfast

 

Start of Parallel Symposia Sessions:

 

8:15 – 10:15         Symposium I

Diverse roles of gonadal hormones in the pathology and treatment of epilepsy in men and women

Chair: Helen Scharfman, PhD (NYU Langone Medical Center)

 

¥   Michael Rogawski MD (UC-Davis) Neurosteroids as drug targets in epilepsy

¥   Neil MacLusky PhD (University of Guelph) The role of gonadal and brain synthesis of estrogen and androgen in regulating brain structure and function

¥   Helen Scharfman PhD (NYU Langone Medical Center) Mechanisms underlying differences in brain excitability in men and women and their relevance to epilepsy

 

8:15 – 10:15         Symposium II

Infections and heart disease

Chair: Sally Huber PhD, Univ. of Vermont

¥   DeLisa Fairweather PhD (Johns Hopkins University) Sex Differences in viral myocarditis; the mouse model and what it tells us

¥   Madeleine Cunningham PhD (University of Oklahoma) Translational Cardiology: from mouse to human clinical myocarditis

¥   Virginia Miller PhD (Mayo Clinic) Sex-specific issues in progression of cardiovascular disease: results from the Kronos Early Estrogen Prevention Study (KEEPS)

 

10:15 – 10:30       Break (posters and exhibits open)

 

Continuation of Parallel Symposia Sessions:

 

10:30 – 12:30       Symposium III

Psychoimmunology of mental illness (in memory of S. Zalcman)

Chairs: Kevin Beck PhD (University of Medicine & Dentistry of NJ/East Orange VA Med Center), and Gretchen Neigh PhD (Emory University)

 

¥   Kevin Beck PhD (UMDNJ/EOVAMC) Suppression of sensory reactivity by cytokines: An unexplored mechanism of behavioral depression in females

¥   Gretchen Neigh PhD (Emory University) Expression of HIV-1 causes depressive-like behaviors and decreased cell genesis in the dentate gyrus of adolescent female rats: role of non-viral neuroinflammation

¥   Anna Marsland PhD RN (University of Pittsburgh) Gender differences in stimulated cytokine production following acute psychological stress

 

10:30 – 12:30       Symposium IV

Sex Differences in Cardiac Arrhythmias

Chair: Glenna Bett PhD (University of Buffalo)

¥   Glenna Bett PhD (University of Buffalo) Sex differences in arrhythmia susceptibility: drugs, subunits, and systems

¥   Guy Salama PhD (University of Pittsburgh) Mapping sex differences in the spatial heterogeneity of cardiac electrophysiology

¥   Randall Rasmusson PhD (University Buffalo) Pregnancy: Sex dependent reversible hypertrophy and action potential prolongation

 

12:30 – 2:30         Lunch (posters and exhibits open)

 

Continuation of Parallel Symposia Sessions:

 

2:30 – 4:30           Symposium V

Clinical Considerations of Sex and Gender in Clinical Practice: Promise, Potential, and Pitfalls

Chair: Marjorie Jenkins MD (Texas Tech Health Sciences University)

¥   Marjorie R. Jenkins MD (Texas Tech Health Sciences University) "Sexxing" of Diseases Matters in Caring for the Aging Patient

¥   Kim Templeton MD (University of Kansas) Aging Joints: Applying the "Sex and Gender" Lens to Arthritis Management

¥   Bradley Miller MD/PhD (Texas Tech Health Sciences University) The Aging Brain: Sex-Based Biases in Neurodegenerative Diseases – Clinical and Research Aspects

 

2:30 – 4:30           Symposium VI

Sex and Gender in Cardiovascular-Renal Physiology and Pathophysiology

Chair: Jane Recklehoff PhD (University of Mississippi Medical Center)

¥   Jennifer Sasser PhD (University of Mississippi Medical Center) Relaxin in renal physiology and disease

¥   Jennifer Sullivan PhD (Georgia Health Sciences University) Immune system regulation in males and females

¥   Michael Ryan PhD (University of Mississippi Medical Center) Mechanisms responsible for hypertension and renal injury in a model of lupus erythematosus

 

4:30 – 5:30           Special Guest Lecture

Alice Dreger PhD (Northwestern University) The use of prenatal dexamethasone for congenital adrenal hyperplasia

 

 

5:30 – 8:00           Poster Session II

 

SATURDAY, April 27th

7:30 - 8:15            Breakfast

 

Continuation of Parallel Symposia Sessions:

 

8:15 – 10:15         Symposium VII

Pain Management in Cancer

Chair: Karen Berkley (Florida State University)

¥   Patrick Mantyh PhD (Univ. Arizona) Mechanisms of bone cancer: sex differences?

¥   Ann OÕMara PhD RN (National Cancer Institute) Cancer pain, palliative care, and quality of life: sex differences?

¥   Paul Farquhar-Smith MB, BChir (Royal Marsden NHS Foundation Trust) Cancer chemotherapy and pain: sex differences?

 

8:15 – 10:15         Symposium VlII

Sex differences in gene expression

Chair: Christine Disteche PhD (University of Washington)

¥   R. Hal Scofield MD (University of Oklahoma Health Sciences Center) X-chromosome aneuploidies explain the sex-bias of lupus and SjogrenÕs syndrome

¥   Jun Xu PhD (Washington State University) Mouse models for an X-linked intellectual disability syndrome

¥   Art Arnold PhD (UCLA) The X and Y chromosomes both contribute to fundamental sex differences in metabolism and obesity

 

10:15 – 10:30       Break

 

Continuation of Parallel Symposia Sessions:

 

10:30 – 12:30       Symposium IX

Causes and consequences of sex differences in multiple sclerosis

Chairs: R. Hal Scofield MD (University of Oklahoma Health Sciences Center) and Sabra Klein PhD (Johns Hopkins University)

¥   Shannon Dunn PhD (University of Toronto) Molecular mechanisms of androgen-dependent protection in rodent models of multiple sclerosis

¥   Cory Teuscher PhD (University of Vermont) Sex chromosomal influences on susceptibility to experimental allergic encephalomyelitis

¥   Deborah Walder PhD (CUNY – Brooklyn College)  Neuromodulators of multiple sclerosis and psychiatric illness: The roles of sex, stress, and hormones

 

10:30 – 12:30       Symposium X

Influence of Sex/Sex Hormones on the GutÕs Role as Guardian of Health

Chair: Lisa Kilpatrick, PhD (UCLA)

¥   Edwin Deitch MD (UMDNJ) Gut injury and multiple organ dysfunction syndrome: Modulation by sex and sex hormones

¥   Veena Taneja PhD (Mayo Clinic/University of Illinois) Sex differences in gut microbiome and risk for rheumatoid arthritis

¥   Meredith Hullar PhD (Hutchinson Cancer Research Center) Human gut microbiome and nutrition

 

Conclusion of Parallel Symposia Sessions

 

12:30 – 2:30         Lunch

 

2:30 – 4:30           Plenary Symposium XI

Centers for Sex Difference Research

Chair: Janine Clayton MD (NIH: Office of Research on WomenÕs Health )

¥   Emeran Mayer MD (UCLA) Chronic pain and the brain – Do sex differences matter?

¥   Wendy Kohrt PhD (University of Colorado School of Medicine) Sex differences of bio-energetics

¥   Jill Barnes PhD (Mayo Clinic) Sex differences in cerebrovascular function

¥   Jeff Henderson MD (Washington University School of Medicine) Infection and the microbiome: Are there sex differences?

 

4:30 – 5:30           Capstone Lecture

Eric Vilain MD/PhD (UCLA) Gender and genetics of sexual development

 

5:30 – 6:30           General OSSD membership meeting

 

7:00 PM               Awards Banquet